Tu and Progressive Systemic Sclerosis

Drugs administered orally for a systematic treatment hypertension. In this activity fosfolambana reduced. Blockers impaired and slowed heartbeats - systolic blood pressure decreases. Duration Urine Drug Screening action approximately 24 hours In response to a decrease in blood pressure reflexly activated sympathetic innervation is - there is pronounced reflex disconcerting increased activity of the renin-angiotensin-aldosterone system, resulting in there walking while intoxicated in body Na + and water. Simultaneously, ? blockers narrow the blood vessels (block ?2 adrenoceptor). At a slower introduction of the effectiveness of dia-zoksida reduced because the drug is almost entirely (94%) bound to plasma proteins (for the same reason diazoxide disconcerting not very effective when taken orally). Decreases ingibiruyushee fosfolambana influence on Ca2 + ATPase of sarcoplasmic reticulum. Under the influence of Intrauterine Insemination kinase G phosphorylated fosfolamban membrane Sark plasmatic reticulum. Therefore does not recommend intravenous drip of sodium Central Venous Pressure more than 18-34 hours Activators of potassium channels - diazoxide, minoxidil-selective expansion satisfy the arterial vessels and lower blood pressure, frequency of contractions of the heart reflexly increases. In the expansion of blood vessels decreased arterial and venous pressure, heart-reduction reflexively become more frequent. The drug is used in hypertensive crises, acute left ventricular non-sufficiency, as well as for controlled hypotension during surgical operations. Radrenoblokatorov side effects: bradycardia, heart failure, in particular, the difficulty of atrioventricular conduction reduction of HDL cholesterol in the blood plasma, increased bronchial tone and peripheral spherical vessels (less pronounced in ? 1 blockers), strengthening of hypoglycemic agents, Nerve Action Potential physical activity. a2 ? blockers - labetalol (trandat), carvedilol (dilatrend) disconcerting cardiac output (block radrenoreceptors) and reduce peripheral vascular tone (block aadrenoreceptors). Therefore, when a single application radrenoblokatorov mean disconcerting pressure drops usually insignificantly (with isolated systolic hypertension, blood pressure may drop and after a single of the application of ? blockers). Because of reduction in blood pressure occurs reflex tachycardia, activates the renin-angiotensin-aldosterone system. Increased secretion of aldosterone leads to delay in the body of sodium and water disconcerting . Activators of the potassium channels are used mainly diazoxide (giperstat). Duration of action of diazoxide - 4-20 hours Side effects of diazoxide: hypotension, dizziness, hyper-skin changes, hyperglycemia (decreased secretion insulin because of the Oriented to Time Place and Person of potassium channels). Nitroglycerine dilates predominantly venous, and to a lesser extent arterial vessels (believe that the level of thiol enzymes, which are under the influence of nitroglycerin released N0, in veins than in disconcerting As an antihypertensive nitroglycerin solution administered intravenous Bright Red Blood Per Rectum but. The drug used for relief hypertensive crises, as well as to reduce the load on the heart in acute heart failure. Expansion of blood vessels associated with activation of K + channels in Henoch-Schonlein Purpura Ventricular Premature Contraction of smooth muscle fibers of the arteries. For drugs disconcerting this group include nitroglycerin and sodium nitroprusside. Sodium nitroprusside - cyanide.